Abstract:
Objective To analyze survival rates of registered cases of cervical cancer based on hospital in Nantong Cancer Hospital from 2002 to 2014 in order to provide basis for the evaluation of prognosis of cervical cancer.
Methods Active follow-up and passive follow-up methods were used to obtain the information on the survival outcomes of hospitalized patients with cervical cancer from Qidong and Haimen in a hospital-based cancer registry. Follow-up ended on 31 March 2016. Survival probability was estimated using the lifetable method, and comparison was made by Gehan statistics.
Results The outcomes of 432 patients were identified in the follow-up of 452 cases from Qidong and Haimen, with a follow-up rate of 95.58%, and a loss rate of 4.42% (20 cases). The average age of the first-hospitalization was (51.59 ±7.07) years old. The most commonly affected ages were 40-59 years old, accounting for 63.89%.The 1-, 3-, 5-, and 10-year observed survival (OS) rate of cervical cancer were 88.43%, 72.74%, 66.58% and 58. 01%, respectively. The 5-year OS rates of cervical cancer at age groups of 0-39, 40-49, 50-59, 60-69, 70+years were 68.17%, 75.77%, 68.57%, 54.52% and 43.42%, respectively. There were significant differences in overall OS rates at two age groups: 0-39 and 60-69 years old (Gehan = 6.144,
P=0.013); 40-49 and 60-69 years old (Gehan = 4.624,
P=0.032). Patients from Qidong seem to have experienced better survival than those patients from Haimen for the 1-, 3-year OS rates, while the 5-, 10-year OS rates seem little higher in patients from Haimen, but no significant differences were found (
P>0.05).
Conclusion There were no significant differences in overall OS rates between patients with cervical cancer from Qidong city and Haimen city, but the singnificant differences exist among age groups. Due to the high follow-up rate of patients, this study fully reflects the comprehensive effect of the treatment of Qidong-Haimen patients with cervical cancer patients at our hospital.