Abstract: Objective To explore the management mode and effects of the women and children's public health programs of Women And Children's Health Care Hospital of Hunan Province.Methods Based on the structure-process-result analysis method, the management strategies of the women and children's public health programs were summarized and analyzed from the aspects of organizational structure, resource allocation, regulations, system activities and results.Results Comprehensive measures promoted the efficient implementation of the programs, including the establishment of a three-level organization for quality management, the establishment of multidisciplinary program teams, the guarantee of working hours and salary of health workers, the reporting of public health adverse events, the monthly project progress, and the organization of seminars of project key issues. In 2017, the coverage, frequency and quality of training and supervision for public health programs increased compared with the same period of last year. The integration of health care and clinical practices was deeper, and the quality management works related to the program was more standardized. In 2015-2017, the main women and children's health indicators in Hunan Province have gradually improved, and the maternal mortality rate, the mortality rate of children under 5 years old, and the incidence of birth defects have decreased year by year.The major public health programs for women and children achieved remarkable effectiveness.Conclusion The management mode of the women and children's public health program performed well, effectively improving the quality and effectiveness of the program.Through continuous improvement, it will provide a strong guarantee for the women and children's public health programs to benefit more women and children.