Abstract: Objective To evaluate the effect of two types of cervical cancer screening programs and provide basis for decisionmaking.Method Through the comparative analysis of early diagnosis rate, detection rate, average cost of early case detection and early detection cost index(EDCI), two types of cervical cancer screening program were evaluated.Result In general, the primary screening rate of "HPV test screening program"(1.83%) was higher than that of "Cytological test screening program"(0.59%),P<0.05. There was no significant difference in the early diagnosis rate between the two screening programs(P=0.089). The average cost of early cases and the cost coefficient of early detection in the "HPV test screening program" were lower than that in the "Cytological test screening program".Conclusion From the perspective of "screening more early cancer patients at a lower cost", the "HPV test screening program" is better than the "Cytological test screening program".