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2014-2019年大连市农村地区宫颈癌筛查数据分析

姜志丹, 赵艳霞, 徐坤鹏, 马莉, 程霞, 郭菲菲

姜志丹, 赵艳霞, 徐坤鹏, 马莉, 程霞, 郭菲菲. 2014-2019年大连市农村地区宫颈癌筛查数据分析[J]. 中国妇幼卫生杂志, 2021, 12(1): 11-16. DOI: 10.19757/j.cnki.issn1674-7763.2021.01.003
引用本文: 姜志丹, 赵艳霞, 徐坤鹏, 马莉, 程霞, 郭菲菲. 2014-2019年大连市农村地区宫颈癌筛查数据分析[J]. 中国妇幼卫生杂志, 2021, 12(1): 11-16. DOI: 10.19757/j.cnki.issn1674-7763.2021.01.003
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JIANG Zhi Dan, ZHAO Yan Xia, XU Kun Peng, MA Li, CHENG Xia, GUO Fei Fei. Analysis of cervical cancer screening results of rural women in Dalian City from 2014 to 2019[J]. CHINESE JOURNAL OF WOMEN AND CHILDREN HEALTH, 2021, 12(1): 11-16. DOI: 10.19757/j.cnki.issn1674-7763.2021.01.003
Citation: JIANG Zhi Dan, ZHAO Yan Xia, XU Kun Peng, MA Li, CHENG Xia, GUO Fei Fei. Analysis of cervical cancer screening results of rural women in Dalian City from 2014 to 2019[J]. CHINESE JOURNAL OF WOMEN AND CHILDREN HEALTH, 2021, 12(1): 11-16. DOI: 10.19757/j.cnki.issn1674-7763.2021.01.003
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2014-2019年大连市农村地区宫颈癌筛查数据分析

  • 1. 辽宁省庄河市妇幼保健计划生育服务中心, 大连 116400;

  • 2. 中国疾病预防控制中心妇幼保健中心, 北京 100081;

  • 3. 大连医科大学公共卫生学院, 大连 116044;

  • 4. 大连市妇幼保健院, 大连 116021

Analysis of cervical cancer screening results of rural women in Dalian City from 2014 to 2019

  • 1. Zhuanghe Maternal and Child Health and Family Planning Service Center, Zhuanghe City, Dalian 116400, China;

  • 2. National Center for Women and Children's Health, China CDC, Beijing 100081, China;

  • 3. Dalian Medical University, School of Public Health, Lushunkou District, Dalian 116044, China;

  • 4. Dalian Maternal and Child Health Care Hospital, Shahekou District, Dalian 116021, China

摘要

    摘要
  • 摘要: 目的 分析2014-2019年大连市农村地区宫颈癌检查项目数据,了解大连市农村地区宫颈癌筛查情况,评价不同初筛方法的检出效果,为进一步做好宫颈癌防治工作提供科学建议。方法 数据来源于妇幼重大公共卫生服务项目信息直报系统中2014-2019年大连市农村地区宫颈癌筛查数据,初筛方法包括宫颈细胞学检查(巴氏涂片、液基细胞学检查)和HPV检测,采用χ2检验比较不同初筛方法和不同年份的初筛阳性率、宫颈癌和癌前病变检出率、早诊率等指标。结果 2014-2019年共有149 918名35~64岁农村妇女进行了免费宫颈癌检查,初筛阳性人数8984人,阳性率为5. 99%;共检出宫颈癌前病变799例,检出率为532. 96/10万;宫颈癌41例,检出率为27. 35/10万;检出早期宫颈癌9例,早诊率为96. 19%。两种不同初筛方法比较:HPV检测初筛阳性率(10. 13%)、低级别鳞状上皮内病变检出率(713. 41/10万)、高级别鳞状上皮内病变检出率(675. 02/10万)、宫颈癌前病变检出率(679. 82/10万)均高于宫颈细胞学检查相应指标值[细胞学初筛阳性率(3. 04%)、低级别鳞状上皮内病变检出率(609. 83/10万)、高级别鳞状上皮内病变检出率(424. 48/10万)、宫颈癌前病变检出率(427. 91/10万)],且差异具有统计学意义(P<0. 05)。结论 2014-2019年大连市农村地区宫颈癌检查成效明显;与宫颈细胞学检查比较,以HPV检测为初筛方法的宫颈癌检查策略可以更好地发现宫颈癌前病变,便于更早进行随访管理。各区县应结合本地实际情况制定科学、高效和可行的宫颈癌检查方案。
    Abstract: Objective To analyze the screening data of cervical cancer in rural areas of Dalian from 2014 to 2019, to understand the screening effect of cervical cancer in rural areas of Dalian, and to evaluate the detection effect of different screening methods, so as to provide scientific suggestions for the prevention and treatment of cervical cancer. Method The data were obtained from the data of the cervical cancer screening in rural areas of Dalian from 2014 to 2019 in the information reporting system of major public health services for women and children. The primary screening methods included cervical cytology tests(Pap smear, liquid-based cytology) and HPV test. The Chi-square test was used to compare the positive rate of primary screening, the detection rate of cervical cancer and precancerous lesions and the early diagnosis rate between different screening methods and years. Result A total of 149,918 rural women aged 35-64 years old were screened for cervical cancer free of charge in 2014-2019. The number of women with positive screening results was 8,984, and the positive rate was 5.99%. 799 were diagnosed as precancerous lesions, and the detection rate was 532.96/105. 41 were diagnosed as invasive cervical cancer, and the detection rate was 27. 35/105. Among them,9 cases were diagnosed as early cervical cancer, and the early diagnosis rate was 96. 19%. The comparison of two different screening methods showed that the positive rate, the detection rate of low-grade squamous intraepithelial lesions, the detection rate of high-grade squamous intraepithelial lesions, and the detection rate of cervical precancerous lesions of HPV test were higher than those of cervical cytology(10.13% vs 3. 04%, 713. 41/105 vs 609. 83/105, 675. 02/105 vs 424. 48/105, and 679. 82/105 vs 427. 91/105, respectively), and the differences between the two screening methods were statistically significant(P< 0. 05). Conclusion The effect of cervical cancer screening in rural areas of Dalian from 2014 to 2019 is obvious. Compared with cervical cytology test, cervical cancer screening strategy based on HPV test as the primary screening method can better detect cervical precancerous lesions and facilitate earlier follow-up management. Each district and county should make a scientific, efficient and feasible cervical cancer screening program strategy according to the local actual situation.
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出版历程
  • 收稿日期:  2020-11-18
  • 网络出版日期:  2023-01-12

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