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未足月胎膜早破与亚临床宫内感染的关系研究

Association analysis between preterm premature rupture of membranes and subclinical intrauterine infection

  • 摘要: 目的 分析未足月胎膜早破(preterm premature rupture of membranes,PPROM)与亚临床宫内感染的关系。方法 采用方便样本法选取2019年1月-2020年12月于河南省安阳市妇幼保健院产科分娩的120例PPROM孕妇纳入研究,回顾性分析孕妇的临床资料,对比发生与未发生亚临床宫内感染孕妇的一般情况,分析PPROM与亚临床宫内感染的关系。结果 120例PPROM孕妇中51例(42.50%)发生亚临床宫内感染;PPROM发生与未发生亚临床宫内感染在年龄、孕次、产次上对比差异无统计学意义(P> 0.05),在破膜孕周、阴道检查次数、期待治疗时间上对比差异有统计学意义(P<0.05);将上述有差异项目代入logistic回归方程,证实破膜孕周、阴道检查次数、期待治疗时间是PPROM发生亚临床宫内感染的影响因素。结论 PPROM在破膜孕周过小、阴道检查次数过多(≥3次)、期待治疗时间> 168 h因素的影响下易发生亚临床宫内感染。

     

    Abstract: Objective To analyze the association between preterm premature rupture of membranes(PPROM) and subclinical intrauterine infection.Methods120 pregnant women were recruited with convenient sampling who gave birth at Anyang Maternal and Child Health Care Hospital with PPROM from January 2019 to December 2020. Their clinical data were analyzed retrospectively. The general condition of pregnant women who did and did not develop subclinical intrauterine infection were compared. The association between PPROM and subclinical intrauterine infection was analyzed.ResultsFifty-one(42. 50%) out of 120 pregnant women with PPROM developed subclinical intrauterine infection. There were no significant differences in the occurrence or absence of subclinical intrauterine infection in terms of age, gravidity, and parity(P> 0. 05), but there were significant differences in terms of gestational week of rupture of membranes, the number of vaginal examinations, and period of expectant management(P< 0. 05). Logistic regression showed that gestational week of rupture of membrane, the number of vaginal examinations and period of expectant management were factors related to the occurrence of subclinical intrauterine infection for PPROM.ConclusionFactors such as smaller gestational week of rupture of membranes, excessive number of vaginal examinations (≥3 times) and period of expectant management > 168 h could cause pregnant women with PPROM to develop subclinical intrauterine infection.

     

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