Abstract: Objective To investigate family nurturing problems and needs of preterm and full-term children, so as to provide evidence for effective family nurturing guidance.Methods Parents of children aged 6-36 months who seek medical care in the Chongqing Health Center for Women and Children were recruited as study subjects from September 2020 to February 2021. Based on gestational age, they were divided into preterm group and full-term group. The main problems of family nurturing and trainings received by parents between 2 groups were compared.Results The questionnaires completed by 276 parents were collected, involving 135children in preterm group and 141 children in full-term group. There were significant differences between 2 groups in terms of picky eating, not eating by themselves, eating less, not drinking milk, patting to sleep, sleeping more in day-time and waking up at night,unable to fall asleep by themself after waking up at night(P< 0. 05). Compared with the full-term group, the proportion of parents in the preterm group who had some difficulty(level two) in child nurturing is higher. The proportions of parents in the preterm group who discussed nurturing issues with professionals and received child development or child behavior training programs(41. 79%, 39. 55%)were significantly higher than that of parents in full-term group(18. 44%, 9. 22%)(P< 0. 05). The proportion of parents in the preterm group who didn't participate child-nurturing course due to inappropriate time was higher(45. 76%) than that of parents in the full-term group(32. 31%), but the proportion of parents who felt no need for training was lower(9. 32%) than that of parents in the full-term group(20. 77%)(P< 0. 05).Conclusion Parents of preterm children meet with more feeding and sleeping problems in the process of nurturing compared with parents of full-term children. They need more professional and targeted help. Parents' nurturing ability should be guided by professional websites or Wechat official accounts based on their needs.