Abstract: Objective To develop an assessment index system of maternal and infant health literacy suitable for pregnant woman. Methods The assessment index system on maternal and infant health literacy among pregnant woman were developed from three dimensions:basic knowledge and perceptions, healthy lifestyle and behavior, and basic skills through literature review and consultation with expert panel. Based on the principle of Delphi method, two-round Delphi consultations were conducted among the experts in related fields to identify the indicators. Results There was 93. 33% of the experts had high professional title,and their average length of work was(20. 6 ± 10. 8) years. Both of the responding and effective rates of two-round consultation questionnaires were 100. 00%,and the authority coefficient of experts was 0. 88 and 0. 89. The Kendall' s W coefficients through first and second round specialist consultation was 0. 131 and 0. 316(all P< 0. 001). After two-round expert consultation,64 qualified assessment indicators were determined based on screening criteria. Conclusion The experts consulted in this study are representative and proactive. Their authority is credible, the degree of coordination is acceptable, and the assessment indicators are reasonable and comprehensive. The development of maternal and infant health literacy assessment index system among pregnant woman lays the foundation for further development of evaluation tool.