Abstract: The guideline aims to facilitate the implementation of the Work Norms for Risk Assessment and Management of Pregnant and Maternal Women enacted by government, and fulfill the needs of health care providers in the fields of maternal and child health care, obstetrics and endocrinology to provide standardized services for prevention and management of thyroid diseases during pregnancy and perinatal period. The guideline recommends a rating system of low, average, moderate high and high risk based on the severity of thyroid disease. The assessment of pregnant risk should be completed dynamically and management measures adjusted timely.