Abstract: Maternal and infant mortality are recognized as comprehensive indicators that reflect a nation's health status and social civilization worldwide. At present, we are facing a series of challenges in the field of maternal and infant health in China, such as the increase of elderly pregnant women, the increase of maternal complications, stillbirth, premature birth, birth defects and other neonatal diseases. Problems including nutrition of pregnant woman, fetus and new born, and psychological health of pregnant woman are prominent. Therefore, maternal and child health care system should be improved with the advance of time, maternal and infant safety measures should be carried out to focus on prevention, rescue capability of maternal near miss should be strengthened, effect evaluation of maternal and infant safety should be scientifically implemented. At the same time, maternal and child health service network in the Chinese context should be reinforced and the service process should be optimized so as to improve the quality of services.