Objective To investigate the situation of maternal hepatitis B infection in Quanzhou, Fujian Province from 2015 to 2022, so as to provide evidence for effective development of intervention measures.

Methods Data were obtained from the information management system for prevention of mother-to-child transmission of HIV, syphilis and hepatitis B. Analysis was conducted to describe the changes in hepatitis B infection rates among 806707 hospitalized deliveries during pregnancy and labour in Quanzhou, the differences in infection rates among various counties (cities and districts), and the differences in the detection of hepatitis B at different stage of pregnancy from 2015 to 2022.

Results The maternal hepatitis B infection rate in Quanzhou showed a downward trend year by year(χ²_trend = 533.27, P < 0.05). The differences in maternal hepatitis B infection rates among various counties (cities and districts) were statistically significant (χ² = 2 144.89, P < 0.05). The total rate of maternal hepatitis B infection was higher in urban than that in rural areas, and the difference was statistically significant (χ² = 19.39, P < 0.05). The testing rate of maternal hepatitis B during pregnancy in Quanzhou showed an upward trend from 2015 to 2022 (χ²_trend = 47 757.32, P < 0.05), while the rate of testing hepatitis B (only during labor) showed a downaward trend year by year (χ²_trend = 36 760.90, P < 0.05), and the rate of hepatitis B infection testing only during labor was higher than that testing during pregnancy, and the difference was statistically significant (χ²= 1 772.61, P < 0.05).

Conclusion Maternal hepatitis B detection rate is relatively high in Quanzhou, Fujian Province. It has been decreased year by year, but it is still at a comparatively high level. Prevention of mother-to-child transmission of hepatitis B should be strengthened continuously so as to further reduce the rate of maternal hepatitis B infection and avoid hepatitis B infection among children.