Abstract: Respiratory viruses are common infectious pathogens in infants, causing significant disease burden on families and society due to their morbidity and mortality. The combination of general preventive measures and specific preventive measures such as vaccines and monoclonal antibodies can effectively prevent the spread of respiratory viruses and reduce the risk of illness. At present, the public’s attention to the prevention of respiratory diseases among vulnerable groups such as infants is increasing. The National Center for Women and Children’s Health, NHC, PRC and the Child Health Branch of the Chinese Preventive Medicine Association organized experts to develop this guide, aiming to enhance the prevention awareness and professional skills of medical personnel at all levels of medical institutions on infant respiratory virus infectious diseases, actively take comprehensive prevention and control measures, promote effective innovative technologies and prevention methods, achieve extensive, efficient and long-term protection for infants, and improve the long-term health level of children.