Objective To preliminarily construct an HPV vaccine health literacy evaluation index system for parents of girls aged 9 to 14 years in China, laying the foundation for the establishment of an evaluation tool to assess the level and weaknesses of HPV vaccine health literacy in this population.

Methods A three-tier indicator system framework was obtained through literature research and expert meetings, and the entries of the three-tier indicators of HPV vaccine health literacy for parents of girls aged 9 to 14 years were screened through 2 rounds of Delphi expert consultation.

Results The effective response rate of two rounds of Delphi expert consultation was 100%, and the coefficient of expert familiarity was 0.85, the coefficient of expert judgment was 0.83, and the coefficient of expert authority was 0.84. In the second round of consultation, the expert harmonization coefficients for the importance, feasibility, and sensitivity of the indicators reached 0.250, 0.248, and 0.221, respectively, with statistically significant differences in the comparison of coefficients ( P < 0.05) . Indicators related to the three aspects of health service utilization, disease prevention, and health promotion, and health literacy was evaluated in four dimensions: access, understanding, evaluation, and application, and 34 three-level indicators were finally obtained.

Conclusion The expert authority and coordination in this study were good, and the screened indicators were reasonable and comprehensive, but further evaluation of reliability and validation of practical application is still needed.