Abstract: Objective To investigate and analyze the incidence and treatment of endometriosis (EMS) in Shenzhen.Methods From January in 2013 to December in 2016, a total of 24 323 female patients were retrospectively selected from the outpatients in our hospital.Among them, the clinical data of EMS patients who were diagnosed were analyzed.Results During 2013-2016, the incidence of EMS in Shenzhen increased significantly (P<0.05).However, there was no significant change in the number of people receiving treatment (P>0.05).In terms of age, the 41-55 age groups showed the highest incidence, followed by the 18-40 age groups.The lowest incidence was showed in patients aged over 56.For the occupation, the incidence of mental workers was higher than that of manual workers.For the EMS type, the mixed type was the most common, followed by peritoneal type.The incidence of ovarian type was lowest.The results of the survey also showed that the situation of continue treatment of EMS in Shenzhen has been significantly improved.The number of EMS patients who were treated by laparoscopic surgery and traditional Chinese medicine was increased gradually.The proportion of using gestrinone capsules and other treatment methods was decreased.Conclusion At present, although the incidence of EMS in Shenzhen showed increasing trend, the situation of clinical treatment has been significantly improved.Moreover, the incidence of EMS in Shenzhen is affected by many kinds of factors.The treatment methods also have been changed.Thus, we recommend that the medical personnel should take measures, further improving the treatment methods, to reduce the incidence of EMS.