Abstract: Objective To provide reference for making plan of women and children's health institutions, by analyzing the change of medical service radius of a tertiary women and children's health care hospital in Guangdong. Method The basic information of inpatients was collected from medical records from 2014 to 2017. The regional distribution of them was described and analyzed by chisquare test.Results 157 654 records were collected. The proportion of the patients from Guangzhou, other cities of Guangdong and other provinces was 76. 08% (119 938/157 654), 21. 87% (4481/157 654) and 2. 05% (3235/157 654), respectively. Most of the patients came from departments of obstetrics, neonatology, pediatricsand gynecology, and most of them lived in Guangzhou. Most of the inpatients from characteristic professional subjects including departments of cardiac surgery, pediatric surgery galactophore, reproductive medicine department were come from places outside Guangzhou. The proportion of this type of patients increased with years.Conclusion During the four years, the medical business growth increased obviously. The medical service radius enlarged gradually, and the brand influence enhanced yearly.