高级检索

产前超声筛查在中孕期胎儿畸形诊断中的应用价值分析

The application value of prenatal ultrasound screening in the diagnosis of fetal malformation during second trimester

    摘要
  • 摘要: 目的 分析产前超声检查对中孕期胎儿畸形筛查的诊断价值。方法 选取2016年6月-2017年6月在深圳市南山区妇幼保健院进行产前超声检查且确定为单胎妊娠的4560例孕妇作为研究对象,以分娩及引产结果为金标准,统计在中孕期产前超声检查畸形胎儿的准确率、灵敏度及特异度。探讨产前超声筛查对中孕期胎儿畸形筛查的应用价值。结果 分娩及引产的4560例胎儿中,胎儿畸形61例,其中心脏异常20例、肾发育异常9例、唇腭裂8例、肺囊腺瘤3例、骨骼异常4例、足内翻3例、膈疝2例、隔离肺2例、脊柱裂3例、腹腔囊肿2例、水肿2例、胼胝体缺失1例、多指畸形2例。胎儿畸形发生率为1.21%。产前超声检查4560例胎儿中,胎儿畸形55例,其中心脏异常18例、肾发育异常9例、唇腭裂7例、肺囊腺瘤3例、骨骼异常4例、足内翻3例、膈疝2例、隔离肺2例、脊柱裂2例、腹腔囊肿2例、水肿2例、胼胝体缺失1例,胎儿畸形发生率为1.21%。差异无统计学意义(P>0.05),产前超声诊断胎儿畸形准确率为99.4%、灵敏度为73.8%、特异度为99.8%。结论 中孕期产前超声能够筛查多种胎儿畸形,具有较高的胎儿畸形检出率,可减少漏诊,具有重要的临床价值。

     

    Abstract: Objective To analyze the diagnostic value of prenatal ultrasound screening in the diagnosis of fetal malformation during second trimester.Methods At total of 4560 cases of pregnant women who received prenatal ultrasound examination and were diagnosed as single pregnancy in our hospital from June, 2017 to June, 2016 were selected as the research subjects. The accuracy, sensitivity and specificity of prenatal ultrasound examination for fetal malformation during second trimester were statistically analyzed.The gold standard was the result of delivery and induced labor. The application value of prenatal ultrasound screening in the diagnosis of fetal malformation during second trimester was to be explored.Results Among the 4560 fetuses, 61 cases of fetal malformation were confirmed after birth or induced labor. They included 20 cases of cardiac abnormalities, 9 cases of renal dysplasia, 8 cases of cleft lip and palate, 3 cases of pulmonary cystadenoma, 4 cases of skeletal abnormalities, 3 cases of varus, 2 cases of diaphragmatic hernia, 2 cases of pulmonary sequestration, 3 cases of 2 cases of spina bifida, 2 cases of celiac cysts, 2 cases of edema, 1 cases of agenesis of the corpus callosum and 2 cases of multi finger malformation. The incidence of fetal malformation was 1.21%. Among the 4560 fetuses, 55 cases of fetal malformation were diagnosed by prenatal ultrasound examination. They included 18 cases of cardiac abnormalities, 9 cases of renal dysplasia, 7 cases of cleft lip and palate, 3 cases of pulmonary cystadenoma, 4 cases of skeletal abnormalities, 3 cases of varus, 2 cases of diaphragmatic hernia, 2 cases of pulmonary sequestration, 2 cases of spina bifida, 2 cases of abdominal cysts, 2 cases of edema and 1 cases of the absence of corpus callosum. The detection rate of fetal malformation was 1.21%. There was no statistical difference between the results of prenatal ultrasound examination and gold standard (P> 0.05). The accuracy of prenatal ultrasonographic diagnosis of fetal malformation was 99.4%, the sensitivity was 73.8% and the specificity was 99.8%.Conclusion Prenatal ultrasound examination can screening many kinds of fetal malformation during second trimester and has a high detection rate of fetal malformation. It can reduce the missed diagnosis and has important clinical value.

     

    • HTML全文
    • 参考文献(0)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回