Abstract: Objective To describe the general situation of breast cancer screening objects and evaluate risk factors of rural women in Guangdong province.Methods Descriptive analysis method was used to describe the general status of screening objects, and Logistic regression model was used to evaluate risk factors of breast cancer among rural women.Results Logistic regression showed that risk factors of breast cancer among rural women in Guangdong were later primiparous, higher BMI and immediate family cancer history, and the protective factor was later menarche age.Conclusion The occurrence of breast cancer among rural women in Guangdong were related with the female physiology and reproduction, body mass index, and immediate family cancer history.