Abstract: Objective To investigate and analyze the iodine nutrition status of pregnant women in Dongguan and its influencing factors.Methods A total of 900 pregnant women who were admitted to Nanfang and Honghua Hospital Obstetrics and Gynecology during the study period from September 2012 to January 2016 were selected. The professional investigators collected the general information of patients and collected the early morning urine samples to determine the level of salt and iodine. And, the Logstic multivariate analysis was used to obtain the influencing factors of iodine nutrition status in pregnant women.Results The proportion of low urinary iodine, normal urinary iodine and high urinary iodine of pregnant women in urban area, suburban area and rural areas in Dongguan had statistically significant differences (P< 0.05). The results of univariate analysis showed that the educational level, labor intensity, consumption of seafood, meat and eggs, and awareness of iodine nutrition were the influencing factors of iodine nutrition status among pregnant women in Dongguan (P< 0.05). The multivariate Logistic analysis showed that high education level was the protective factor of high iodine nutritional status, and heavy physical labor intensity and regularly eating seafood were the risk factors of high iodine nutritional status.Conclusion The overall level of iodine nutrition in pregnant women in Dongguan is poor. 46.65%pregnant women are in iodine deficiency state. Higher education is the protective factor of iodine nutrition, heavy physical labor intensity and eating seafood are the risk factors of high iodine nutritional status.