Survey on HBV infection in maternal and the First dose of hepatitis B vaccination in Anxi county hospital 2015-2017

Objective To investigate the first dose and timely vaccination of HBs Ag positive mothers and their newborns in anxi county hospital in 2015-2017.Methods All of the pregnant women who gave birth in the hospital and their newborns from 2015 to 2017 were selected. The age, permanent residence, the history of hepatitis B vaccination and the status of hepatitis B infection of the mothers was analyzed. And the first dose vaccination rate and timely rate of the newborns were analyzed.Results ① From 2015 to 2017, a total of 14760 pregnant women were in hospital for childbirth, and 1221 were positive of HBsag. Then infection rate was 8.27%. ②The HBs Ag positive rate of women without hepatitis B vaccination history was significantly higher than the HBs Ag positive rate of women with hepatitis B vaccination history. ③ Under the age of 30 years old, the positive rate of HBs Ag increased with the age.At the same time, hepatitis B infection was mainly concentrated between the ages of 25 and 35 years old, and the infection rate was greater than 2.0%. ④The positive rate of HBs Ag among rural women was significantly higher than that of urban women. ⑤ From 2015 to 2017, the first dose vaccination rate and timely rate of county level hospitals were higher than that of the overall county. The reasons that affected the timely first injection rate of the county level hospitals were mainly premature delivery and underweight.Conclusion The maternal HBs Ag positive rate is high in 2015-2017.It is necessary to strengthen the prenatal screening and management of pregnant women, improve the management of hepatitis B vaccination and timely vaccination system for newborns, and effectively improve the blocking effect of hepatitis B in mothers and infants.