Effect of subclinical hypothyroidism on pregnancy outcome and thyroid function of neonates
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Graphical Abstract
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Abstract
Objective To investigate and analyze the effect of pregnancy outcome and thyroid function of neonates in pregnancy with subclinical hypothyroidism (hypothyroidism).Methods 55 cases pregnant women with subclinical hypothyroidism treated in our hospital February 2017-February 2018 were included in the study group. At the same time, 60 cases normal pregnant women were included in the control group. The pregnancy outcomes and thyroid function of newborn were compared.Results The cesarean section rate (29.09%) in the study group and (8.33%) in the control group were statistically significant (P<0.05). The incidence rates of premature birth, fetal distress and low birth weight were higher in the study group than those in the control group (P<0.05). By measurement, the incidence rate of subclinical hypothyroidism and TSH level of neonates in both groups were different, which had statistical significance (P<0.05).Conclusion The subclinical hypothyroidism may have an impact on pregnancy outcome and thyroid function of newborn babies. Prenatal monitoring should be carried out to ensure the safety of mother and baby.
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