Study on the pathogen,clinical characteristics and treatment of lobar pneumonia in children

Objective To analyze the clinical characteristics,pathogen composition and drug sensitivity test results of children with lobar pneumonia,and to provide reference for the selection of treatment regimens.Methods The clinical data of 140 children with lobar pneumonia admitted to our hospital from December 2016 to December 2018 were analyzed retrospectively.The distribution and composition of pathogenic bacteria in children,basic data of the children(sex,age,disease season,vital signs,clinical symptoms,laboratory indicators,imaging manifestations),treatment plan and clinical efficacy were analyzed to explore the treatment plan of lobar pneumonia in children.Results The results showed that the gender of the children with lobar pneumonia was mainly girls,and the age was mainly under 7 years old.The disease can occur in Guangdong all the year round,and the seasonality is not obvious.Among the 140 cases,the mean time of onset of clinical symptoms at the time of imaging diagnosis and the time of etiological diagnosis was(4.35±0.42) days and(6.14±1.03) days,respectively.A total of 152 pathogens were detected in blood culture,respiratory tract culture and humoral culture,mainly mycoplasma pneumoniae,followed by streptococcus pneumoniae and staphylococcus aureus,and 14 other pathogenic bacteria were detected.No pathogen was detected in 16 cases.Mixed infection was found in 24 cases.There were 59 cases with shadow in the left middle and lower lung field,56 cases with large patchy shadow in the right middle and lower lung field,and 25 cases with large shadow in the right middle and upper lung field.Twenty-four children with atelectasis were diagnosed.All children were treated with empirical antimicrobial agents after diagnosis,and some children were treated with anti-inflammatory drugs and improved immune function according to inflammation and immune function,or with bronchial lavage for critically ill patients.All the treatment obtained good clinical efficacy.Conclusion Children with lobular pneumonia are younger There were poor specificity of clinical symptoms and signs before imaging diagnosis.Mixed pathogen infection is common.c It is necessary to closely observe the changes of the disease,adopt comprehensive treatment measures to control the infection and inflammation as soon as possible,improve the immune function,avoid affecting the function of other organs,and improve the clinical efficacy.