Analysis of HPV infection among 35576 female patients in Nangning,Guangxi

Objective To analyze the infection status and genotype distribution of human papillomavirus (HPV) among females in Nanning.Methods A retrospective analysis was made on 35 576 patients who underwent HPV test in Guangxi Maternal and Child Health Care Hospital from July 2016 to May 2019. Female cervical secretions were collected,and the genotypes of HPV were determined by polymerase chain reaction (PCR).Results Of the 35 576 female patients,5661 cases infected with HPV,and the total detection rate was 15. 88%. The number of patients with HPV16 infection,HPV18 infection and other high-risk HPV subtypes infection were 1046 (2. 94%) 、447 (1. 26%) and 4738 (13. 32%),respectively. There was no statistically significant difference in HPV infection rate among different years (P > 0. 05). The detection rates of HPV infection in the five age groups (lower than 26 years old,26-30 years old,31-40 years old,41-50 years old and older than 50 years old) were 21. 93%,12. 16%,14. 83%,14. 38% and 7. 62%,respectively.Conclusions The infection rate of HPV was 15. 88% among the female population in Nanning,the infection rate of HPV16,HPV18 and other high-risk HPV subtypes was 2. 94%,1. 26% and 13. 32%,respectively. The infection ratewas the highest in the age group of lower than 26 years old (21. 93%),while the infection rate was the lowest in the women older than 50 years old (7. 62%). More attention should be focused on screening and preventing HPV infection in high-risk population.