The analysis on the status and influencing factors of childrenwith congenital syphilis in Jilin province

Objective To discuss the status and influencing factors of childrenwith congenital syphilis in Jilin.Methods A casecontrol study was used analyzed the exposure of related factors in children with congenital syphilis. Logistic regression was used to analyze the influencing factors of children with congenital syphilis to correct the confounding factors.Results Unvarable analysis showed there were statistical differences in the titer of RPR and abnormal conditions and antisyphilic medicine of pregnancy and the birth weight of newborns between the two groups(P<0.05). Multivarable analysis showed the risk factors of congenital syphilis including high titer of RPR and abnormal conditions of pregnancy. Anti-syphilic medicine of pregnancy and higher birth weight of newborns were protective factors.Conclusion The risk of congenital syphilis is high for children if the mother had high titer of RPR and abnormal conditions of pregnancy and if not had anti-syphilic medicine of pregnancy and low birth weight of newborns. Children whose mothers with high titer of RPR,abnormal conditions during pregnancy and parturition,without anti-syphilis treatment and children with low birth weight are more likely to develop congenital syphilis.