Advanced Search
WANG Wei, TANG Wei Ping, ZHU Na Ling, LUO Ya Li, WANG Li Ling, LIU Zhi Hua. Case report of using pegylated interferon alpha-2a in the treatment of child with chronic hepatitis B[J]. CHINESE JOURNAL OF WOMEN AND CHILDREN HEALTH, 2021, 12(4): 73-77. DOI: 10.19757/j.cnki.issn1674-7763.2021.04.016
Citation: WANG Wei, TANG Wei Ping, ZHU Na Ling, LUO Ya Li, WANG Li Ling, LIU Zhi Hua. Case report of using pegylated interferon alpha-2a in the treatment of child with chronic hepatitis B[J]. CHINESE JOURNAL OF WOMEN AND CHILDREN HEALTH, 2021, 12(4): 73-77. DOI: 10.19757/j.cnki.issn1674-7763.2021.04.016

Case report of using pegylated interferon alpha-2a in the treatment of child with chronic hepatitis B

  • Objective To report and analyze a case of using pegylated interferon alpha-2 a injection(Peg-IFN-α-2 a) in the treatment of a child with chronic hepatitis B(CHB). Methods Peg-IFN-α-2 a was used to treat a CHB child with positive hepatitis B e antigen(HBe Ag). Clinical and laboratory data were collected and analysed during treatment and follow-up. Results After 24 weeks of treatment with Peg-IFN-α-2 a,both HBe Ag and hepatitis B surface antigen(HBs Ag) seroconversion preceded,and hepatitis B virus(HBV) DNA dropped from 6. 20 lg IU/ml to the line that undetected. Aminotransferase(ALT) decreased to normal level,and HBV surface antibodies(anti-HBs) were present. The child experienced fever and neutropenia symptoms during treatment. Conclusion Using Peg-IFN-α-2 a as antiviral drug might provide a safe and effective treatment option for children with CHB. It would provide theoretical evidence for subsequent development of antiviral treatment protocol for them.
  • loading

Catalog

    Turn off MathJax
    Article Contents

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return