Association analysis between preterm premature rupture of membranes and subclinical intrauterine infection

Objective To analyze the association between preterm premature rupture of membranes(PPROM) and subclinical intrauterine infection.Methods120 pregnant women were recruited with convenient sampling who gave birth at Anyang Maternal and Child Health Care Hospital with PPROM from January 2019 to December 2020. Their clinical data were analyzed retrospectively. The general condition of pregnant women who did and did not develop subclinical intrauterine infection were compared. The association between PPROM and subclinical intrauterine infection was analyzed.ResultsFifty-one(42. 50%) out of 120 pregnant women with PPROM developed subclinical intrauterine infection. There were no significant differences in the occurrence or absence of subclinical intrauterine infection in terms of age, gravidity, and parity(P> 0. 05), but there were significant differences in terms of gestational week of rupture of membranes, the number of vaginal examinations, and period of expectant management(P< 0. 05). Logistic regression showed that gestational week of rupture of membrane, the number of vaginal examinations and period of expectant management were factors related to the occurrence of subclinical intrauterine infection for PPROM.ConclusionFactors such as smaller gestational week of rupture of membranes, excessive number of vaginal examinations (≥3 times) and period of expectant management > 168 h could cause pregnant women with PPROM to develop subclinical intrauterine infection.