Depression among pregnant women undergoing prenatal screening and the influence factors

Objective To compare depression among high and low risk pregnant women undergoing prenatal screening, and explore factors associated with depression at different pregnant periods.Methods A total of 924 pregnant women undergoing prenatal screening were recruited, and they were divided into high-risk group(231 cases) and low-risk group(693 cases). Self-rating Depression Scale was used to assess the level of depression before prenatal screening, after prenatal screening, late pregnancy(≥ 28 weeks) and 6 weeks postpartum. The pregnancy outcomes of the two groups were investigated at 6 weeks postpartum.Results The overall detection rate of depression among pregnant women undergoing prenatal screening was 18.3%, of which 30.5% in high-risk group and 9.2 in low-risk group. Depression detection rates were higher in the high-risk group than those in the low-risk group both after prenatal screening and 6 weeks postpartum(χ²=62.556, P<0.001; χ²=27.389,P<0.001). Before prenatal screening, physical labor was a protective factor for maternal depression(OR=0.380, 95%CI:0.170-0.850); After prenatal screening, high risk of prenatal screening was a risk factor for depression(OR=7.302, 95%CI:4.019-13.267); At late pregnancy, depression pre-and post-prenatal screening was a risk factor for depression(OR=12.911,95%CI:4.316-38.622; OR=10.601,95%CI:4.854-23.195). At 6 weeks postpartum, high risk of prenatal screening, depression after prenatal screening and depression at late pregnancy were risk factors for depression(OR=3.117, 95%CI:1.618-6.003; OR=4.510, 95%CI:2.126-9.566; OR=7.999,95%CI:3.306-19.353).Conclusion High risk pregnant women diagnosed by prenatal screening have a high incidence of adverse mood and pregnancy outcomes, and close attention should be paid to their mental health after the results of prenatal screening and at 6 weeks postpartum, and targeted psychological intervention should be given to them.