Vitamin D levels among children aged 0－10 in Women’s and Children’s Health Hospital of Yunfu from 2019 to 2021, Guangdong Province

Objective To investigate the 25（OH）D level in children aged 0－10 years old in Yunfu, Guangdong, so as to provide scientific evidence for vitamin D supplement guidance in this area.

Methods The serum 25（OH）D levels of 6 208 children who underwent physical examination in the Women’s and Children’s Health Hospital of Yunfu from January 2019 to October 2021 were analyzed retrospectively. The effects of gender, age and season on the serum 25（OH）D levels were statistically analyzed.

Results The average level of serum 25（OH）D in 6 208 children aged 0－10 years old was（41.40 ± 13.44）ng/mL. There was no significant difference in the level of serum 25 （OH） D between different genders （P > 0.05）. The proportion of boys with 25 （OH） D deficiency was lower than that of girls, and the proportion of boys with 25 （OH） D sufficiency was higher than that of girls（χ² = 19.057,P < 0.001）. With the increasing of children’s age, the serum 25 （OH） D level decreased. The average level of infants 0－< 1（49.05 ± 14.17）ng/mL was the highest and that of 7－10 age group was the lowest （31.09 ± 7.65）ng/mL. There was significant difference in the serum 25 （OH） D level between different age groups （F = 350.097,P < 0.001）. The serum 25 （OH） D level in spring was the highest and that in autumn was the lowest. The serum 25 （OH） D level in the four seasons were statistically different （F = 45.809,P < 0.001）.

Conclusion Nutritional status of vitamin D in preschool children should be paid attention to, children’s outdoor activities should be increased appropriately, and family education should be carried out actively.