Citation: | LEI Jin Meng, NONG Zheng, GUAN Hai Bin, ZENG Ding Yuan, JIANG Ming Juan, ZHOU Bo. Analysis on surveillance data of perinatal birth defects in Liuzhou, Guangxi Zhuang Autonomous Region, 2018 − 2022[J]. CHINESE JOURNAL OF WOMEN AND CHILDREN HEALTH, 2024, 15(1): 43-47. DOI: 10.19757/j.cnki.issn1674-7763.2024.01.008 |
To explore the trend and epidemiological features of perinatal birth defects in Liuzhou, Guangxi Zhuang Autonomous Region from 2018 to 2022, so as to provide evidence for scientific prevention and control of birth defects.
Retrospective research method was used to analyze perinatal birth defect surveillance data, which were born in various midwifery institutions from 28 weeks to 7 days postpartum at Liuzhou, Guangxi Zhuang Autonomous Region, 2018 − 2022.
Totally, 3 406 infants with birth defects were found among 212 475 perinatal newborns from 2018 to 2022, and the incidence of birth defects was 160.30/10 000. The incidence of birth defects first declined and then rose. The average incidence of birth defects of boy was 176.06/10 000, which was significantly higher than that of girl (142.43/10 000) (χ2 = 36.821, P < 0.001). Higher incidence of birth defects showed in the offspring of mothers aged ≥ 35 years (201.91/10 000) compared to younger mothers (P < 0.05). The incidence of birth defects in the offspring of mothers who had 1 pregnancy (174.44/10 000) and 1 birth (189.21/10 000) was higher than that of mothers who had ≥ 2 pregnancies and births (P < 0.05). The incidence of birth defects in multiple births (433.66/10 000) was higher than that in singleton births (152.65/10 000) (P < 0.05). The top 5 birth defects were congenital heart diseases (68.95/10 000), multiple fingers/toes (31.06/10 000), hypospadias (9.15/10 000), syndactyly (9.08/10 000) and other outer ear deformities (8.71/10 000).
The incidence of perinatal birth defects remains at a relatively high level in Liuzhou, 2018 − 2022. Congenital heart diseases and multiple fingers/toes are the most common birth defects. It is recommended to further improve the construction of the three-tier prevention system for birth defect prevention and control.
[1] |
姜文婧,陈雨晴,杨佳汇,等. 新生儿出生缺陷现状及干预措施实施进展[J]. 中国儿童保健杂志,2021,29(12):1317-1320.
|
[2] |
方俊,徐昊立,吴云涛,等. 广东省2016 — 2021年出生缺陷医院监测结果分析[J]. 中国优生与遗传杂志,2023,31(3):433-438.
|
[3] |
李敏,甘露,王宝珠. 陕西省2016 — 2020年围生儿出生缺陷监测分析[J]. 中国优生与遗传杂志,2022,30(10):1699-1702.
|
[4] |
梁丽芳,韦洁,韦慧,等. 2013 — 2019年广西地区围生儿出生缺陷监测结果分析[J]. 中国妇幼保健,2022,37(1):133-136.
|
[5] |
刘永红,秦艳,磨静佳,等. 南宁市出生缺陷的发生率、流行病学特征及影响因素[J]. 广西医学,2019,41(12):1536-1540.
|
[6] |
Yang X,Zeng J,Gu Y,et al. Birth defects data from hospital-based birth defect surveillance in Guilin,China,2018 − 2020[J]. Front Public Health,2022,10:961613. doi: 10.3389/fpubh.2022.961613
|
[7] |
Kosowan L,Mignone J,Chartier M,et al. Maternal social and economic factors and infant morbidty,mortality,and congenital anomaly:are there association?[J]. Fam Community Health,2019,42(1):54-61. doi: 10.1097/FCH.0000000000000211
|
[8] |
修新红,袁丽,王晓明,等. 出生缺陷影响因素的病例对照研究[J]. 中华妇产科杂志,2011,46(7):6.
|
[9] |
李亮亮,杨兰,王称,等. 2015 — 2020年甘肃省围产儿出生缺陷时空分布特征分析[J]. 疾病监测,2023,38(4):466-472.
|
[10] |
陈瑾,李蓉,陈燕珊. 潮州市2019 — 2020年围产儿出生缺陷监测分析[J]. 中国卫生标准管理,2022,13(10):9-12.
|
[11] |
蒋武,黄永全,覃頔,等. 南宁市2009 — 2014年围产儿出生缺陷性别差异研究[J]. 中国初级卫生保健,2016,30(1):33-35.
|
[12] |
徐道仙,施晓华,宋艳萍,等. 新生儿出生缺陷风险和缺陷类型与父母年龄的相关性分析[J]. 中国妇幼保健,2022,37(21):4043-4046.
|
[13] |
岳晓倩,陈华. 2014 — 2019年常熟市围产儿出生缺陷与产妇年龄构成关系[J]. 江苏预防医学,2021,32(1):98-99.
|
[14] |
王春燕,龚景进,李思慧,等. 高龄妊娠对胎儿疾病的影响[J]. 中华产科急救电子杂志,2016,5(3):173-177.
|
[15] |
陆华媛. 2017 — 2020年南宁市某城区围产儿出生缺陷现状分析[D]. 南宁:广西医科大学,2021.
|
[16] |
Cho GJ,Jung US,Kim HY,et al. Women with multiple gestations have an increased risk of development of hypertension in the future[J]. BMC Pregnancy Childb,2021,21(1):510. doi: 10.1186/s12884-021-03992-2
|
[17] |
刘巧凤,刘兆董,李仁善,等. 双胎妊娠并发子痫前期临床研究进展[J]. 中国综合临床,2020,36(5):413-416.
|
[18] |
苏慧明. 减胎术对多胎妊娠孕妇妊娠期并发症及子代的影响[J]. 现代诊断与治疗,2021,32(5):786-787.
|
[19] |
姚慧,曾萼,雷利志,等. 2000 — 2015年广西出生缺陷综合防控效果分析[J]. 广西医学,2017,39(8):1210-1214.
|
1. |
朱楚玲,林丽卿. 2013—2022年福建省泉州市831819例围产儿出生缺陷监测结果分析. 中国妇幼卫生杂志. 2024(02): 11-15 .
![]() | |
2. |
杜雪铭,程志伟,张猛,王彭彭,梁肖,杜真,胡孟彩,乔艳华,徐锋,赵冰. 2011—2020年河南省围产儿出生缺陷发生率及变化趋势分析. 现代预防医学. 2024(13): 2360-2363 .
![]() | |
3. |
潘淑娟,武芸,秦福丽,边艳霞,王莉. 2018—2022年临汾市围生儿出生缺陷变化趋势分析. 中国优生与遗传杂志. 2024(08): 1702-1706 .
![]() | |
4. |
刘雨,张金婵,李碧云,欧惠朗,徐昊立. 2015—2022年广东省河源市出生缺陷监测结果分析. 中国妇幼卫生杂志. 2024(05): 45-48 .
![]() | |
5. |
丁志芬,王丽,谈笑,施秀颖,王分霞,毕丽军,曹雯. 常州市钟楼区出生缺陷医院监测结果及影响因素分析. 保健医学研究与实践. 2024(08): 84-89 .
![]() | |
6. |
朱茂灵,赵士博. 南宁市出生缺陷综合防控治理状况及对策研究▲. 广西医学. 2024(11): 1735-1740 .
![]() | |
7. |
李桂华,包晓玲,赵智. 围生儿出生缺陷诊疗现状和相关影响因素多中心调查研究. 中国优生与遗传杂志. 2024(12): 2621-2625 .
![]() |