Analysis of the applications effect of comprehensive PMTCT intervention services for HIV-infected pregnant women in Hunan Province in 2012-2016

Objective This study aims to systematically evaluate the service status and variation trend of PMTCT intervention in Hunan Province in recent years by collecting data on the condition of HIV-infected pregnant women in Hunan Province in 2012-2016, which include consultation, detection, childbirth, treatment and follow-up, in order to provide reference for further normalizing and developing PMTCT services.Methods To analyze the status of PMTCT intervention services for HIV-infected pregnant women and infants born in Hunan province from 2012 to 2016, and got the data from National IPMTCT Surveillances System.Results During 2012 to 2016, the consultation rate of HIV-infected pregnant women in Hunan province was 97. 9%, 98. 6%, 99. 21%, 99. 5% and 99. 8%, respectively (χ_Trend²=17, 897. 608, P=0. 000); the detection rate for HIV was 96. 9%, 98. 5%, 99. 2%, 99. 5% and 99. 7%, respectively (χ_Trend²=27, 842. 453, P=0. 000); the medication rate of HIV-infected pregnant women was 56. 8%, 57. 0%, 60. 2%, 67. 2% and 76. 7%, respectively (χ_Trend²=11. 546, P=0. 001); the medication rate for the antiviral prevention of children born by HIV-infected pregnant women was 68. 2%, 76. 0%, 71. 6%, 80. 0% and 87. 0%, respectively (χ_Trend²=11. 860, P=0. 001); the early diagnosis rate of children born by HIV-infected pregnant women was 53. 6%, 69. 5%, 80. 5%, 83. 2% and 93. 5%, respectively (χ_Trend²=56. 614, P=0. 000); the ratio of children over 18 months old who underwent HIV antibody tests was 22. 5%, 22. 5%, 25. 8%, 37. 0% and 43. 6%, respectively (χ_Trend²=17. 090, P=0. 000); the ratio of children who underwent more than six follow-up was 21. 1%, 21. 6%, 25. 8%, 37. 0% and 43. 6%, respectively (χ_Trend²=31. 992, P=0. 000).Conclusions During 2012 to 2016, great progress has been achieved in the consultation rate and detection rate for preventing the maternal-neonatal transmission of AIDS in Hunan Province, However, a certain gap still remains from national demands in terms of medication for HIVinfected pregnant women, antiviral medication for children born by HIV-infected pregnant women, the supply of follow-up and relevant detection for children, as well as the maternal-neonatal transmission rate of AIDS. Various measures need to be further implemented to better normalize and carry out PMTCT services, and reduce the maternal-neonatal transmission rate of AIDS.